Find hotels in East Prairie, MO from CA $94

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for East Prairie hotels

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (743 reviews)
"Parking was good, staff was great "
United States
Corey
New Orleans Inn Portageville

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (408 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is CA $96
CA $106 total
includes taxes & fees
Feb 24 - Feb 25
The Riverstone Hotel Charleston-Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (623 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is CA $85
CA $94 total
includes taxes & fees
Mar 3 - Mar 4
Super 8 by Wyndham Charleston/Sikeston East MO

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (381 reviews)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is CA $83
CA $99 total
includes taxes & fees
Mar 12 - Mar 13
Hospitality House Union City I 69 / US 51

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (467 reviews)
"Nice in clean room"
United States
Jayla
The price is CA $94
CA $108 total
includes taxes & fees
Mar 15 - Mar 16
Reelfoot Lake Inn

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (105 reviews)
"Convenient "
United States
Marcelle
The price is CA $87
CA $97 total
includes taxes & fees
Feb 24 - Feb 25
Eagle Inn Charleston

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (352 reviews)
"The rooms are big and the property is spotless!"
United States
debbie
The price is CA $98
CA $116 total
includes taxes & fees
Mar 15 - Mar 16
Sleep Inn at Discovery Park of America

Travel Inn

Travel Inn
2.5 star property
Marston
6.0 out of 10, (118 reviews)
"Had a great time loved it "
United States
Shyianne
The price is CA $68
CA $78 total
includes taxes & fees
Mar 20 - Mar 21
Travel Inn

MainStay Suites Union City, TN

MainStay Suites Union City, TN
2.5 star property
Union City
8.6 out of 10, Excellent, (44 reviews)
"Very clean room, friendly staff! I would highly recommend this place! "
United States
Lydia
The price is CA $130
CA $154 total
includes taxes & fees
Feb 24 - Feb 25
MainStay Suites Union City, TN

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (552 reviews)
"Very clean nice staff and well run "
United States
zach
The price is CA $98
CA $117 total
includes taxes & fees
Feb 24 - Feb 25
Country Hearth Inn & Suites Union City

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (495 reviews)
"Nice room"
Mexico
José Ricardo
The price is CA $92
CA $109 total
includes taxes & fees
Mar 8 - Mar 9
Quality Inn Union City US 51

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,005 reviews)
"As always it was a perfect visit"
United States
John
The price is CA $129
CA $148 total
includes taxes & fees
Mar 1 - Mar 2
Drury Inn & Suites Sikeston, MO

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (48 reviews)
"Room clean bed comfortable, breakfast simple but good."
United States
James
The price is CA $92
CA $105 total
includes taxes & fees
Feb 25 - Feb 26
Super 8 By Wyndham Marston

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (172 reviews)
"Spotless , friendly staff."
United States
Gail
The price is CA $171
CA $203 total
includes taxes & fees
Feb 26 - Feb 27
Hampton Inn Union City

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,001 reviews)
"Everything was excellent"
United States
James
The price is CA $93
CA $106 total
includes taxes & fees
Feb 25 - Feb 26
Days Inn and Suites by Wyndham Sikeston

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (595 reviews)
"Great place"
United States
Misty
The price is CA $86
CA $98 total
includes taxes & fees
Feb 24 - Feb 25
Super 8 by Wyndham Sikeston/Miner Area

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (313 reviews)
"The room was spacious & clean. The complimentary breakfast was nice. Very quiet place and next to a unique tourist attraction."
United States
Angela
The price is CA $141
CA $168 total
includes taxes & fees
Mar 1 - Mar 2
Holiday Inn Express & Suites Union City by IHG

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (123 reviews)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is CA $73
CA $87 total
includes taxes & fees
Feb 24 - Feb 25
Country Yard Inn and Suite

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (739 reviews)
"Room was clean. Fairly quiet room. Front desk was kind. Would stay here again. ."
United States
Becky
The price is CA $83
CA $94 total
includes taxes & fees
Feb 24 - Feb 25
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (60 reviews)
"Clean rooms great staff"
United States
IRA
The price is CA $150
CA $170 total
includes taxes & fees
Mar 5 - Mar 6
Fairfield Inn & Suites by Marriott Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Recent Reviews in East Prairie

More cheap stays in East Prairie

Hotels in East Prairie with star rating

Frequently asked questions

What is the best area to stay in East Prairie?
The best area to stay in East Prairie is near Main Street, particularly around the intersection with Washington Street.

This central part of East Prairie offers the most convenience for visitors. It's where you'll find the majority of local businesses, including eateries and shops. The area is quite walkable, allowing you to easily explore the town's core.

For travellers looking for a straightforward and practical base, staying near Main Street is ideal.
When is the best time to go to East Prairie?
The best time to visit East Prairie, Missouri, is typically during the spring (April to May) and autumn (September to October) months.

These seasons offer the most pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the town and its surrounding natural areas. Spring brings blooming flowers and lush greenery, while autumn showcases beautiful fall foliage, particularly along the nearby Mississippi River.

For those interested in local festivities, visiting in September allows you to experience the annual Sweet Corn Festival, a significant event for the town.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in East Prairie.
How can I save on a East Prairie hotel booking with Expedia?
Members always get our best prices. Find our best East Prairie hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a East Prairie hotel?
Prices for hotels in East Prairie often vary, but you can find a great deal from CA $94 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia