Find hotels in East Prairie, MO from CA $78

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Our top choices for East Prairie hotels

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (561 reviews)
"Very clean nice staff and well run "
United States
zach
The price is CA $86
CA $102 total
includes taxes & fees
Apr 18 - Apr 19
Country Hearth Inn & Suites Union City

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (757 reviews)
"The staff was great very helpful and friendly "
United States
Javier
The price is CA $72
CA $78 total
includes taxes & fees
Apr 19 - Apr 20
New Orleans Inn Portageville

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.2 out of 10, Very good, (60 reviews)
"The property is beautiful! The rooms are terrific! Staff is amazing! Totally recommend!! "
United States
Sue
The price is CA $97
CA $111 total
includes taxes & fees
May 16 - May 17
Super 8 By Wyndham Marston

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
"Very nice for overnight stay"
United States
Scott
The price is CA $141
CA $162 total
includes taxes & fees
May 4 - May 5
Drury Inn & Suites Sikeston, MO

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (71 reviews)
"Nice quiet hotel "
United States
Steven
The price is CA $151
CA $171 total
includes taxes & fees
May 14 - May 15
Fairfield Inn & Suites by Marriott Sikeston

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (766 reviews)
"Very nice place, very nice stay! They were out of cream cheese for the bagels at breakfast though.:-)"
United States
Mark
The price is CA $90
CA $102 total
includes taxes & fees
Apr 20 - Apr 21
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,000 reviews)
"Very nice folks who manage the hotel!!"
United States
Jane
The price is CA $123
CA $141 total
includes taxes & fees
Apr 26 - Apr 27
Best Western Plus Sikeston I-55

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (480 reviews)
"Ok one night stay."
United States
David
The price is CA $89
CA $102 total
includes taxes & fees
Apr 20 - Apr 21
Reelfoot Lake Inn

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very good, (503 reviews)
"Overall, a decent stay. No fancy bells or whistles, exactly what was advertised and delivered. Only issue of note was that the room smelled of body odder when we stayed. "
United States
John
The price is CA $108
CA $129 total
includes taxes & fees
Apr 26 - Apr 27
Quality Inn Union City US 51

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (284 reviews)
"Amenities, microwave, refrigerator,iron and iron board,Shower soap options "
United States
Maurice
The price is CA $103
CA $115 total
includes taxes & fees
Apr 24 - Apr 25
Quality Inn Cairo I-57

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (411 reviews)
"Clean "
United States
Chris
The price is CA $126
CA $140 total
includes taxes & fees
Apr 18 - Apr 19
The Riverstone Hotel Charleston-Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,000 reviews)
"Business friendly, clean room staff very friendly, accommodating."
United States
Janice
The price is CA $95
CA $109 total
includes taxes & fees
Apr 22 - Apr 23
Days Inn and Suites by Wyndham Sikeston

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (376 reviews)
"Great stay. "
United States
Paul
The price is CA $129
CA $153 total
includes taxes & fees
Apr 20 - Apr 21
Sleep Inn at Discovery Park of America

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (390 reviews)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is CA $78
CA $93 total
includes taxes & fees
Apr 23 - Apr 24
Hospitality House Union City I 69 / US 51

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (629 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is CA $89
CA $99 total
includes taxes & fees
Apr 21 - Apr 22
Super 8 by Wyndham Charleston/Sikeston East MO

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (459 reviews)
"Clean rooms, friendly staff and convenient location."
United States
Mark
The price is CA $138
CA $157 total
includes taxes & fees
May 3 - May 4
Holiday Inn Express & Suites Sikeston Southwest by IHG

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (178 reviews)
"Spotless , friendly staff."
United States
Gail
The price is CA $173
CA $205 total
includes taxes & fees
Apr 19 - Apr 20
Hampton Inn Union City

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (16 reviews)
"This hotel was great. Good location. Awesome staff. Hopefully I get the opportunity to stay here again."
United States
Jason
The price is CA $174
CA $197 total
includes taxes & fees
May 7 - May 8
TownePlace Suites by Marriott Sikeston

Travel Inn

Travel Inn
2.5 star property
Marston
6.0 out of 10, (119 reviews)
"Had a great time loved it "
United States
Shyianne
The price is CA $75
CA $86 total
includes taxes & fees
Apr 21 - Apr 22
Travel Inn

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"The hotel needs a renovation. For the price I didn’t expect much, but it feels neglected."
United States
Britani
The price is CA $75
CA $84 total
includes taxes & fees
May 2 - May 3
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

The Mississippi River near Hannibal, Missouri, USA

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Hotels in East Prairie with star rating

Frequently asked questions

What is the best area to stay in East Prairie?
The best area to stay in East Prairie is near Main Street, particularly around the intersection with Washington Street.

This central part of East Prairie offers the most convenience for visitors. It's where you'll find the majority of local businesses, including eateries and shops. The area is quite walkable, allowing you to easily explore the town's core.

For travellers looking for a straightforward and practical base, staying near Main Street is ideal.
When is the best time to go to East Prairie?
The best time to visit East Prairie, Missouri, is typically during the spring (April to May) and autumn (September to October) months.

These seasons offer the most pleasant weather, with mild temperatures and less humidity, making it ideal for exploring the town and its surrounding natural areas. Spring brings blooming flowers and lush greenery, while autumn showcases beautiful fall foliage, particularly along the nearby Mississippi River.

For those interested in local festivities, visiting in September allows you to experience the annual Sweet Corn Festival, a significant event for the town.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in East Prairie.
How can I save on a East Prairie hotel booking with Expedia?
Members always get our best prices. Find our best East Prairie hotel deals by joining Expedia's free travel rewards program today. As a member, you can unlock instant savings and member perks when you're logged in to your account. Another tip is to book your hotel and flights together on Expedia, where bundling can result in significant savings.
How much is the nightly rate at a East Prairie hotel?
Prices for hotels in East Prairie often vary, but you can find a great deal from CA $78 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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