
Find hotels in East Prairie, MO from CA $78
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Family friendly
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Our top choices for East Prairie hotels

Country Hearth Inn & Suites Union City
Country Hearth Inn & Suites Union CityUnion City
8.6 out of 10, Excellent, (561 reviews)
The price is CA $86
CA $102 total
includes taxes & fees
Apr 18 - Apr 19

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very good, (757 reviews)
The price is CA $72
CA $78 total
includes taxes & fees
Apr 19 - Apr 20

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.2 out of 10, Very good, (60 reviews)
The price is CA $97
CA $111 total
includes taxes & fees
May 16 - May 17

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is CA $141
CA $162 total
includes taxes & fees
May 4 - May 5

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (71 reviews)
The price is CA $151
CA $171 total
includes taxes & fees
May 14 - May 15

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (766 reviews)
The price is CA $90
CA $102 total
includes taxes & fees
Apr 20 - Apr 21

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,000 reviews)
The price is CA $123
CA $141 total
includes taxes & fees
Apr 26 - Apr 27

Reelfoot Lake Inn
Reelfoot Lake InnTiptonville
7.2 out of 10, Good, (480 reviews)
The price is CA $89
CA $102 total
includes taxes & fees
Apr 20 - Apr 21

Quality Inn Union City US 51
Quality Inn Union City US 51Union City
8.4 out of 10, Very good, (503 reviews)
The price is CA $108
CA $129 total
includes taxes & fees
Apr 26 - Apr 27

Quality Inn Cairo I-57
Quality Inn Cairo I-57Cairo
6.6 out of 10, (284 reviews)
The price is CA $103
CA $115 total
includes taxes & fees
Apr 24 - Apr 25

The Riverstone Hotel Charleston-Sikeston
The Riverstone Hotel Charleston-SikestonCharleston
6.8 out of 10, (411 reviews)
The price is CA $126
CA $140 total
includes taxes & fees
Apr 18 - Apr 19

Days Inn and Suites by Wyndham Sikeston
Days Inn and Suites by Wyndham SikestonSikeston
7.2 out of 10, Good, (1,000 reviews)
The price is CA $95
CA $109 total
includes taxes & fees
Apr 22 - Apr 23

Sleep Inn at Discovery Park of America
Sleep Inn at Discovery Park of AmericaUnion City
9.2 out of 10, Wonderful, (376 reviews)
The price is CA $129
CA $153 total
includes taxes & fees
Apr 20 - Apr 21

Hospitality House Union City I 69 / US 51
Hospitality House Union City I 69 / US 51Union City
6.8 out of 10, (390 reviews)
The price is CA $78
CA $93 total
includes taxes & fees
Apr 23 - Apr 24

Super 8 by Wyndham Charleston/Sikeston East MO
Super 8 by Wyndham Charleston/Sikeston East MOCharleston
6.8 out of 10, (629 reviews)
The price is CA $89
CA $99 total
includes taxes & fees
Apr 21 - Apr 22

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (459 reviews)
The price is CA $138
CA $157 total
includes taxes & fees
May 3 - May 4

Hampton Inn Union City
Hampton Inn Union CityUnion City
9.6 out of 10, Exceptional, (178 reviews)
The price is CA $173
CA $205 total
includes taxes & fees
Apr 19 - Apr 20

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (16 reviews)
The price is CA $174
CA $197 total
includes taxes & fees
May 7 - May 8

Travel Inn
Travel InnMarston
6.0 out of 10, (119 reviews)
The price is CA $75
CA $86 total
includes taxes & fees
Apr 21 - Apr 22

Eagle Inn Charleston
Eagle Inn CharlestonCharleston
6.6 out of 10, (106 reviews)
The price is CA $75
CA $84 total
includes taxes & fees
May 2 - May 3
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular East Prairie attractions
Learn more about East Prairie
Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

Top East Prairie Hotel Reviews
Recent Reviews in East Prairie

Super 8 by Wyndham Sikeston/Miner Area
8/10 Good
More cheap stays in East Prairie

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
The price is CA $90 per night from Apr 20 to Apr 21
CA $90
CA $102 total
Apr 20 - Apr 21
includes taxes & fees
8.4/10 Very Good! (766 reviews)
Hotels in East Prairie with star rating

3 Star Hotels
7 properties

2 Star Hotels
23 properties
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